What vitamins should not be taken together

You Won't Believe What Vitamins Should Not Be Taken Together!


We all know how important it is to have a rainbow on our plates, from vibrant fruits packed with Vitamins A and C to wholesome grains full of Vitamin B. Balanced vitamin intake keeps our bodies at their best.

But did you know what vitamins should not be taken together? It might surprise you since we’re always told to eat a variety of foods for max health benefits. Yep, certain vitamins don't mix well and can cause side effects. In this blog post, we’ll explore what vitamins should not be taken together and why. So, you can eat the rainbow - just not all at once!

Let's Dive into Vitamin Combos

Guess what? Some vitamins need a buddy to be effective, while others just don’t get along. It's all about synergism and antagonism.

So, what's the deal with synergism and antagonism? Synergism happens when two vitamins team up like best friends, boosting each other's effects. It's like one plus one equals three! 

Antagonism, on the other hand, is like when two people just can't get along, no matter what. When certain vitamins are taken together, they can interfere with each other’s absorption or effectiveness. This can lead to negative effects, such as decreased nutrient absorption or even vitamin buildup which can cause side effects. 

Tag-Team Duos: Vitamins That Work Together

So, let's break down synergism with a few examples.  Vitamin D helps your body absorb calcium, making them a dynamic duo for bone health. It does this by activating the enzymes in charge of calcium absorption.

In the same breath, Vitamin C is famous for boosting your immune system, aiding in the absorption of iron, and acting as a powerful antioxidant. Think of succulent citrus fruits to earthy sweet potatoes - this vitamin can be easily added to your meal. Studies suggest that Vitamin C helps your body absorb non-heme iron (the type of iron found in plant-based foods and supplements).

Vitamins That Don't Buddy Up: The Surprising Non-Duos

On the flip side, we have antagonism. 

Calcium + Iron: A No-Go

A prime example is calcium and iron; it’s like they’re competing for the same spotlight, and neither one gets to shine as brightly. Iron is your body's BFF for making red blood cells and keeping your energy levels up. It does this by carrying oxygen from your lungs to the rest of your body. It's also essential for a boost in brain power - making it an absolute must for overall health.

From thick Greek yogurt to sardines and salmon, calcium sources are everywhere. This nutrient is what keeps your teeth and bones strong, protecting you from osteoporosis (brittle bones). But when iron and calcium share a meal or dietary supplement, they can interfere with each other's absorption. Calcium can prevent your body from absorbing iron properly - meaning you may not be getting as much of the red blood cell-making powerhouse as you think. So, keep some time between popping your calcium supplement and iron supplements to get the best of both worlds.

Vitamin C and Copper:  A Feud Beyond Time

We’ve all heard about the importance of Vitamin C for our immune health, but when it comes to pairing it with copper, things can get a bit tricky. While they both play vital roles in our body, their antagonistic relationship can cause some unwanted side effects.

Vitamin C, known scientifically as ascorbic acid, is renowned for its ability to enhance immune function, promote skin health through collagen synthesis, and act as a potent antioxidant. On the other hand, copper is crucial for forming red blood cells, maintaining healthy bones and nerves, and supporting immune function. Despite both being crucial nutrients, their relationship is more like frenemies than friends.

When taken together in large amounts, Vitamin C and copper come together and create a Fenton reaction (cool name, right?). The Fenton reaction can cause oxidative stress, damaging cells and DNA, which can even cause damage to the kidneys. So, while both nutrients are great for our health, it's better to keep them apart when taking supplements.

Iron + Zinc:  A Full-On Hate Relationship

Iron is at it again, but this time with Zinc. Zinc is a trace mineral that helps your body's immune system and metabolism. Think of seafood and legumes rich in zinc. But when the two come together, Iron can inhibit the amount of zinc absorbed by your body and vice versa.

That's why, here at First Day, we decided not to include iron in our gummy multivitamins. We focus on effective absorption and prioritize the most common nutrient deficiencies!

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Knowing all of this can either ramp up your vitamin combo game or make you feel like giving up on vitamins altogether.

What Makes Vitamin Combos Click?

Okay, so now that we know some vitamins don't get along, let's dig into what makes everything work smoothly. Spoiler alert: It's not as complicated as you think, but it's crucial!

What Your Body Specifically Needs

Everyone's nutritional needs are different, influenced by things like age, gender, lifestyle, and health conditions. For example, the NIH says older adults have different needs and often need more vitamin D and B12 because their bodies absorb them less efficiently. Similarly, pregnant women usually need more iron and folic acid, so they need to take a folic acid or iron supplement. The growing baby needs folic acid to build its nervous system such as its spinal cord. These are just a few examples - so consulting with your doctor or nutritionist is essential.

Food vs. Pills: The Great Debate

Here’s the age-old question: should you get your vitamins from food, supplements, or both?

Firstly, getting vitamins from a well-balanced diet is always the goal. Why? Because whole foods give you more than just the basic vitamins and minerals - they’re also packed with fiber, antioxidants, and other important nutrients that work together to keep you healthy. For instance, an orange isn’t just a source of Vitamin C; it’s also got potassium, fiber, and several other compounds that contribute to your overall wellness.

But let's be real. Sometimes, it’s hard to get everything you need from food alone. Enter yummy multivitamins. These little dietary supplements can fill in the gaps when your diet isn’t cutting it. For example, if you’re living somewhere with long, dark winters, a Vitamin D supplement can be a game-changer since it’s known as the “sunshine vitamin.”

First Day multivitamins are yummy gummy treats loaded with essential vitamins and nutrients, making staying healthy a breeze! Each delicious gummy has an optimal amount of each vitamin and mineral, formulated to work together just like your body would want them to - without any unnecessary excess. Plus, no artificial sweeteners or coloring—just healthy goodness, including a blend of 12 organic fruits and veggies.

The key is balance and knowing that while supplements can help, they shouldn’t replace a healthy diet. Think of supplements as your vitamin safety net - they catch what you miss but shouldn't be your first line of defense.

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Ultimately, the food vs. pills debate isn’t about choosing one over the other; it’s about finding a combination that works for you. And remember, always chat with your doctor before starting any new supplement regimen to make sure it’s safe and beneficial for your unique needs.

How Well Do You Absorb Vitamins?

Absorption rates can vary wildly depending on several factors, including the form of the vitamin and your overall health. For example, unlike water-soluble vitamins, fat-soluble vitamins like A, D, E, and K are better absorbed when taken with food containing fat. This reinforces that a well-balanced diet is critical for optimal nutrient absorption.

Health Perks and Pitfalls of Vitamins

But let's not forget an often overlooked aspect of vitamins - what happens when you don’t get enough or take too much of them?

Risk of Deficiency or Toxicity

First up, let's talk about the risk of not getting enough vitamins (deficiency) versus getting too many (toxicity). It's all about striking the right balance. For example, according to a study published in the Best Practice & Research Clinical Endocrinology & Metabolism journal, vitamin D deficiency can lead to weakened bones and an increased risk of fractures. On the other hand, too much vitamin D can cause calcium buildup, leading to nausea and vomiting. Keeping your intake within recommended limits is crucial to avoiding these pitfalls.

So, Remind Us... What Vitamins Should Not Be Taken Together?

It all boils down to finding that balance between food and supplements to give your body the nutrients it needs. Think of vitamins and supplements as your backup plan—for those times when your diet isn't quite hitting the mark. Remember to consult with a healthcare professional to tailor your vitamin intake to your unique needs.

Ready to make staying healthy fun and easy? First Day gummy multivitamins are the perfect addition to a well-balanced diet and can help fill in those nutrient gaps. Plus, with our organic ingredients and delicious flavors, you'll be looking forward to taking your vitamins every day!

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Archives - 2017 Volume 5, issue 6. (n.d.). Www.ijpab.com. Retrieved June 22, 2024, from https://www.ijpab.com/vol5-iss6a30.php 

van Ballegooijen, A. J., Pilz, S., Tomaschitz, A., Grübler, M. R., & Verheyen, N. (2017). The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. International Journal of Endocrinology, 2017, 1–12. https://doi.org/10.1155/2017/7454376 

Sr, L., & Jd, C. (1980). Interaction of Vitamin C and Iron. Annals of the New York Academy of Sciences. https://pubmed.ncbi.nlm.nih.gov/6940487/ 

American Society of Hematology. (2020). Iron-Deficiency anemia. American Society of Hematology. https://www.hematology.org/education/patients/anemia/iron-deficiency 

Jáuregui-Lobera, I. (2014). Iron deficiency and cognitive functions. Neuropsychiatric Disease and Treatment, 10, 2087. https://doi.org/10.2147/ndt.s72491 

Branch, N. S. C. and O. (2023, May 5). Calcium and Vitamin D: Important for Bone Health. National Institute of Arthritis and Musculoskeletal and Skin Diseases. https://www.niams.nih.gov/health-topics/calcium-and-vitamin-d-important-bone-health#:~:text=Calcium%20does%20more%20than%20build 

Garrick, N. (2022, December). Osteoporosis. National Institute of Arthritis and Musculoskeletal and Skin Diseases. https://www.niams.nih.gov/health-topics/osteoporosis#:~:text=Osteoporosis%20is%20a%20bone%20disease 

Lönnerdal, B. (2010). Calcium and Iron Absorption - Mechanisms and Public Health Relevance. International Journal for Vitamin and Nutrition Research, 80(45), 293–299. https://doi.org/10.1024/0300-9831/a000036 

National Institutes of Health. (2021, March 26). Vitamin C. National Institutes of Health. https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/ 

Jiang, R., Sui, Y., Hong, J., Niimi, M., Yan, Q., Shi, Z., & Yao, J. (2023). The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury. Biomolecules, 13(1), 143–143. https://doi.org/10.3390/biom13010143 

National Institutes of Health. (2022, September 28). Zinc. Nih.gov; National Institutes of Health. https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/ 

Donangelo, C. M., Woodhouse, L. R., King, S. M., Viteri, F. E., & King, J. C. (2002). Supplemental Zinc Lowers Measures of Iron Status in Young Women with Low Iron Reserves. The Journal of Nutrition, 132(7), 1860–1864. https://doi.org/10.1093/jn/132.7.1860 

Dietary Supplements for Older Adults. (n.d.). National Institute on Aging. https://www.nia.nih.gov/health/vitamins-and-supplements/dietary-supplements-older-adults 

Esquivel, M. K. (2022). Nutrition Benefits and Considerations for Whole Foods Plant-Based Eating Patterns. American Journal of Lifestyle Medicine, 16(3), 155982762210759. https://doi.org/10.1177/15598276221075992 

USDA. (2020). FoodData Central. Usda.gov. https://fdc.nal.usda.gov/fdc-app.html#/food-details/169097/nutrients 

Health, N. R. C. (US) C. on D. and. (1989). Fat-Soluble Vitamins. In www.ncbi.nlm.nih.gov. National Academies Press (US). https://www.ncbi.nlm.nih.gov/books/NBK218749/#:~:text=Small%20amounts%20of%20vitamins%20are 

Lips, P., & van Schoor, N. M. (2011). The effect of vitamin D on bone and osteoporosis. Best Practice & Research Clinical Endocrinology & Metabolism, 25(4), 585–591. https://doi.org/10.1016/j.beem.2011.05.002 

Asif, A., & Farooq, N. (2021). Vitamin D Toxicity. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK557876/